@Scott0044
Sort of basing this answer off of your original post...
If you have a Choice Column for your Category and a Choice Column for your Priority in the list (now again, I am considering this the "lookup list" that you would modify as needed to update people and assignments).
LookUp(yourReferenceList,
Category.Value = yourCategoryValue &&
Priority.Value = yourPriorityValue,
'Assigned To'
)
My guess (please expand on your scenario if needed) is that you will have two dropdowns with the Category and Priority - let's call then ddCategory and ddPriority
The Items property for ddCategory would be : Distinct(yourList, Category)
And the Item property for ddPriority would be : Distinct(yourList, Priority)
Then you can lookup the 'Assigned To' person with this formula:
LookUp(yourReferenceList,
Category.Value = ddCategory.Selected.Result &&
Priority.Value = ddPriority.Selected.Result,
'Assigned To'
)