Hi @melkatbry19 ,
Yes you can do this in one flow and add a switch action so if the email is from someone, do these actions, from someone else, do these actions, etc, etc. Inside of those switch cases, you can also add a subject or body conditional action that says, if the subject contains this State, create here, otherwise create here, etc, etc.
That said, the Switch action will handle up to 25 different cases and inside of each of those, you can have additional condition action branching.