You can have as the data that is passed to the Items property in your dropdown, the screen that you want to navigate to. For example, if you have three screens (Screen1, Screen2, Screen3), and you have a dropdown in the first screen, you can set its Items property to the following:
Table({Name:"Go to screen 2", scr: Screen2},{Name:"Go to screen 3", scr: Screen3})And in the OnChange action handler, you would call the Navigate function passing the value of the selected item in the dropdown
Navigate(Dropdown1.Selected.scr, ScreenTransition.Fade)
Hope this helps!