Hi @jorenchristiaen,
Do you need to save the same data from the related record, or do you just need to view the related data? If you just need to view related data, you could create a Quick View form for the related table and add it to your form. The quick view form would show up whenever the Lookup has a selected record populated.
If you need to populate data from a related entity, you can define Attribute Mappings on the 1:N relationship. If on the related record form you have a subgrid to this entity and click + (Add New), when it opens the create new form it will pre-populate the values of the related record including the lookup. Note that this will not auto-populate if you are just creating a new record without coming from the related record.
The other way to populate the fields is with a JavaScript web resource, registered to the OnChange event of the Lookup field. You would retrieve the related record using the Lookup value selected. Then you can set the form values using the related record you retrieved.
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