Hi @EricRegnier , I am not sure if I am doing something wrong.
I used the Upload image control and a separate to use the Patch with.
UploadedImage1 Image property has this formula
I created tow columns on SharePoint called Email Image (Single Line Text) and Profile Image (Image)
LookUp(SPList, 'Email Image' = currUsers.mail).'Profile Image'
On the button I use this formula
Patch(SPList, LookUp(SPList, 'Email Image' = Office365Users.MyProfileV2().mail), { 'Profile Image': UploadedImage1.Image})