Hi@vladimir84,
Combine that with your description, I think you have some misunderstanding with the IsBlank() function and the IsEmpty() function.
The IsBlank() function is used to check if a value is Blank. The IsEmpty() function is used to test whether a table contains any records, in other words, the IsEmpty() function is used to detect if there is no records within a Table.
More details about IsBlank() function and IsEmpty() function, please check the following article:
IsBlank() function and IsEmpty() function
I have a test on my side and the situation is confirmed on my side.
Add a Label and set the Text property as below:
"" = Blank()

Empty string ("") refers to a string that contains no characters.
The Empty string ("") is not equal to Blank. You could see that the above formula would always return false, that is proof.
I assume that there is no "" value within the array data related to the Combo Box, if you want to check if a Combo Box value is Blank, please take a try with the following workaround:
Add a Button and set the DisplayMode property of the Button1 as below:
If(
IsEmpty(ComboBox1.SelectedItems),
DisplayMode.Disabled,
DisplayMode.Edit
)
Add a Label and set the Text property as below:
"filters are active"
Set the Visible property of the Label as below:
If(Button1.DisplayMode=Edit,true,false)
Hope it could help.

Best Regards,
Qi