Re: Trigger (Start/Stop) a flow from sharepoint list
@KrishR
I agree with the suggestions from @eliotcole but want to add some additional thoughts.
I would add an Office 365 Outlook Get Mailtips action to your Flow. You can check the automatic replies message to see if a given user has set "out of office" to on. If there is an out of office message, don't assign an action to that user. That will help prevent the issue that you are trying to solve.
You could also use the Power Automate "run after" settings and set a time out on an action or scope. If a user has not taken action within a specified time, you can escalate the request somehow.
Another option might be for you to re-write you Flow logic. Split it out so that you have a Flow that runs with a recurrence trigger that fires every day. The Flow will check the items in your list and take action as appropriate based on your requirements.
If you can provide a more detailed description of your process, I might be able to provide more specific guidance.